Atletico will take a two-goal lead into next month’s second leg thanks to goals from Gimenez and Godin in an action packed opening 90 minutes to this last-16 tie.
The hosts had a penalty awarded and overturned in an evenly matched first half, but they offered far more of an attacking threat after the restart, squandering a glorious chance through Costa, hitting the crossbar when Griezmann’s attempt was helped onto the crossbar by Szczesny and having a Morata goal ruled out.
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Then came two goals in the space of five minutes towards the end of the game, both scored by Uruguayan centre-backs from set-pieces.
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